BDBM202819 US10245267, Example 651::US10709712, Example 166::US9242969, 166::US9694016, 651

SMILES Cc1ncc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1cc(N2CCOCC2)c(=O)n(C)n1

InChI Key InChIKey=KPZHLNWOKWZIHG-UHFFFAOYSA-N

Data  20 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202819   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM202819(US10245267, Example 651 | US10709712, Example 166 ...)
Affinity DataIC50:  6.93nMpH: 7.5 T: 2°CAssay Description:Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent